TOP CLONOPIN IN ITALIA SECRETS

Hepatic Impairment Following oral administration of just one four mg dose (2 mg hydromorphone immediate-release tablets), mean exposure to hydromorphone (Cmax and AUC∞) is enhanced 4-fold in sufferers with reasonable (Boy or girl-Pugh Team B) hepatic impairment as opposed with subjects with regular hepatic function. As a result of enhanced exposu